SCHEMBL7530338

SCHEMBL7530338

CCCCOC(=O)c1cc(-c2ccc(N)c(C(=O)OCCCC)c2)ccc1N

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.68
HSD17B10 Q99714 2/20 0.68
KDM4E B2RXH2 3/20 0.60
POLB P06746 1/20 0.60
TSHR P16473 8/20 0.58
TDP1 Q9NUW8 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
CYP3A4 P08684 3/20 0.54
LMNA P02545 3/20 0.54
CYP1A2 P05177 3/20 0.54
CYP2C19 P33261 2/20 0.54
CYP2C9 P11712 1/20 0.54
PDE4D Q08499 1/20 0.54
MAPK1 P28482 3/20 0.53
TP53 P04637 1/20 0.53
NPC1 O15118 1/20 0.48
MAPT P10636 1/20 0.48
RAB9A P51151 1/20 0.48
ESR1 P03372 4/20 0.47
CYP2D6 P10635 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5137750 0.88 ALDH1A1 (0.68) ALDH1A1HSD17B10KDM4EPOLBTSHR
SCHEMBL7159501 0.86 ALDH1A1 (0.66) ALDH1A1HSD17B10KDM4EPOLBTSHR
SCHEMBL28326757 0.85 ALDH1A1 (0.68) ALDH1A1HSD17B10KDM4EPOLBTSHR
SCHEMBL11506341 0.85 ALDH1A1 (0.64) ALDH1A1HSD17B10KDM4EPOLBTSHR
SCHEMBL6817217 0.85 ALDH1A1 (0.64) ALDH1A1HSD17B10KDM4EPOLBTSHR
SCHEMBL9073929 0.83 ALDH1A1 (0.64) ALDH1A1HSD17B10KDM4ETSHRL3MBTL1
SCHEMBL13779469 0.83 TSHR (0.60) ALDH1A1HSD17B10TSHRTDP1L3MBTL1
SCHEMBL22773392 0.82 ALDH1A1 (0.69) ALDH1A1HSD17B10KDM4EPOLBTSHR
SCHEMBL5181901 0.82 ALDH1A1 (0.69) ALDH1A1HSD17B10KDM4EPOLBTSHR
SCHEMBL6818803 0.81 ALDH1A1 (0.59) ALDH1A1HSD17B10KDM4EPOLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823459-B1 Disazo pigment composition and printing ink DAINIPPON INK & CHEMICALS (JP) 2002-04-17 EP disclosed
US-5803962-A Disazo pigment composition and printing ink DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-09-08 US disclosed
EP-0823459-A2 Disazo pigment composition and printing ink DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-11 EP disclosed
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 US disclosed