Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL27649164 | 1.00 | LMNA (0.61) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Sebacic Acid SCHEMBL13815498 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Methacrylic Acid SCHEMBL7733879 | 0.97 | TSHR (0.63) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Hexanoate SCHEMBL11309571 | 0.91 | AKR1B1 (0.73) | LMNATSHRAKR1B1SLC22A6GPR84 | |
| Adipic Acid SCHEMBL9751316 | 0.89 | LMNA (0.48) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Decanoic Acid SCHEMBL9474677 | 0.89 | GPR84 (0.74) | LMNATSHRAKR1B1SLC22A6GPR84 | |
| Stearic Acid SCHEMBL28583641 | 0.89 | GPR84 (0.74) | LMNATSHRAKR1B1SLC22A6GPR84 | |
| Stearic Acid SCHEMBL273139 | 0.89 | GPR84 (0.74) | LMNATSHRAKR1B1SLC22A6GPR84 | |
| Hexanoate SCHEMBL28847576 | 0.89 | AKR1B1 (0.70) | LMNATSHRAKR1B1SLC22A6GPR84 | |
| Decanoic Acid SCHEMBL8059157 | 0.89 | GPR84 (0.74) | LMNATSHRAKR1B1SLC22A6GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117050374-A | Thermal expansion microsphere and preparation method thereof | 浙江大学 | 2023-11-14 | — | — | CN | claimed |
| CN-115612163-A | Preparation method of foaming microcapsule | 浙江大学 | 2023-01-17 | — | — | CN | claimed |
| CN-112126389-A | Plasticizer migration resistant aqueous pressure-sensitive adhesive and preparation method thereof | 杭州英创新材料有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-102516435-B | Method for preparing porous material by reversible addition fragmentation chain transfer polymerization of high internal phase emulsion | UNIV ZHEJIANG | 2014-06-04 | — | — | CN | claimed |
| CN-102731704-A | Method for preparing open-cell submicron porous polymer materials by miniemulsion template method | UNIV ZHEJIANG | 2012-10-17 | — | — | CN | claimed |
| CN-102516435-A | Method for preparing porous material by reversible addition fragmentation chain transfer polymerization of high internal phase emulsion | UNIV ZHEJIANG | 2012-06-27 | — | — | CN | claimed |
| CN-101220230-B | Nano-coloring material aqueous dispersions containing polyurethane component and method for producing the same | SHANGHAI HUAMING HI TECH GROUP | 2010-12-01 | — | — | CN | claimed |
| CN-101544712-A | Method for preparing phase-transition capsule dispersion liquid through mini-emulsion polymerization | UNIV ZHEJIANG | 2009-09-30 | — | — | CN | claimed |
| CN-101220230-A | Nano-coloring material aqueous dispersions containing polyurethane component and method for producing the same | SHANGHAI HUAMING HI TECH GROUP (CN) | 2008-07-16 | — | — | CN | claimed |
| WO-2008052265-A1 | A PROTHROMBOGENIC BIOMATERIAL FOR TISSUE REPAIR | QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) | 2008-05-08 | — | — | WO | claimed |
| CN-100348625-C | Process for preparing microcapsule by initiating active fine emulsion polymerization of water-soluble initiating agent | UNIV ZHEJIANG (CN) | 2007-11-14 | — | — | CN | claimed |
| CN-100336834-C | Process for preparing micro capsule of imitating active fine emulsion polymerizing by oil-soluble initiating agent | UNIV ZHEJIANG (CN) | 2007-09-12 | — | — | CN | claimed |
| CN-1693312-A | Process for preparing micro capsule of imitating active fine emulsion polymerizing by oil-soluble initiating agent | UNIV ZHEJIANG (CN) | 2005-11-09 | — | — | CN | claimed |
| CN-1693317-A | Process for preparing microcapsule by initiating active fine emulsion polymerization of water-soluble initiating agent | UNIV ZHEJIANG (CN) | 2005-11-09 | — | — | CN | claimed |
| CN-222170004-U | Array substrate, sounding device and display device | 杭州福斯特电子材料有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-117050374-A | Thermal expansion microsphere and preparation method thereof | 浙江大学 | 2023-11-14 | — | — | CN | disclosed |
| CN-115612163-A | Preparation method of foaming microcapsule | 浙江大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-100348627-C | Method for preparing organic silicon modified propenoic ester copolymer emusion by fine emulsion polymerizing method | UNIV ZHEJIANG (CN) | 2007-11-14 | — | — | CN | disclosed |
| CN-1858076-A | Method for preparing organic silicon modified propenoic ester copolymer emusion by fine emulsion polymerizing method | UNIV ZHEJIANG (CN) | 2006-11-08 | — | — | CN | disclosed |
| CN-1693317-A | Process for preparing microcapsule by initiating active fine emulsion polymerization of water-soluble initiating agent | UNIV ZHEJIANG (CN) | 2005-11-09 | — | — | CN | disclosed |