Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TDP2 | O95551 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | GALK1 | P51570 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5179888 | 0.87 | MAPT (0.46) | MAPTALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL5138337 | 0.75 | MEN1 (0.54) | MAPTALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL5139020 | 0.75 | MEN1 (0.54) | MAPTALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL5138659 | 0.74 | TSHR (0.43) | MAPTALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL5138334 | 0.74 | TSHR (0.43) | MAPTALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL16130571 | 0.68 | CYP3A4 (0.59) | MAPTALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL15430835 | 0.68 | CYP3A4 (0.59) | MAPTALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL14926636 | 0.66 | TDP1 (0.53) | MAPTALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL14926665 | 0.66 | TDP1 (0.53) | MAPTALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL5599951 | 0.65 | TSHR (0.89) | ALDH1A1SMN1; SMN2TSHRLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008037604-A1 | NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2008-04-03 | — | — | WO | claimed |
| WO-2008037604-A1 | NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2008-04-03 | — | — | WO | disclosed |