Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MPI | P34949 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.53 |
| ▸ | FGFR2 | P21802 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139020 | 1.00 | MEN1 (0.54) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL5138334 | 0.87 | TSHR (0.43) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL5138659 | 0.87 | TSHR (0.43) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL9904567 | 0.78 | MAPT (0.78) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL7538581 | 0.75 | PPARG (0.72) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL5138097 | 0.75 | MAPT (0.47) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL14231954 | 0.75 | FGFR1 (0.57) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL14231952 | 0.73 | FGFR1 (0.77) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL16130571 | 0.72 | CYP3A4 (0.59) | KMT2ALMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL15430835 | 0.72 | CYP3A4 (0.59) | KMT2ALMNAMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008037604-A1 | NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2008-04-03 | — | — | WO | claimed |
| WO-2008037604-A1 | NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2008-04-03 | — | — | WO | disclosed |