Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5138659 | 1.00 | TSHR (0.43) | TSHRPPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5138337 | 0.87 | MEN1 (0.54) | TSHRPPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5139020 | 0.87 | MEN1 (0.54) | TSHRPPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5138606 | 0.84 | ALDH1A1 (0.51) | TSHRPPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5138100 | 0.76 | PPARG (0.56) | TSHRPPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5138683 | 0.75 | FFAR1 (0.33) | SMN1; SMN2MEN1KMT2AMAPK1FGFR1 | |
| SCHEMBL5138097 | 0.74 | MAPT (0.47) | TSHRALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL16130571 | 0.71 | CYP3A4 (0.59) | TSHRALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL15430835 | 0.71 | CYP3A4 (0.59) | TSHRALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL14926636 | 0.68 | TDP1 (0.53) | TSHRALDH1A1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008037604-A1 | NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2008-04-03 | — | — | WO | claimed |
| WO-2008037604-A1 | NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2008-04-03 | — | — | WO | disclosed |