Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.47 |
| ▸ | FAP | Q12884 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15206677 | 0.79 | DPP4 (0.65) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL3697380 | 0.79 | DPP4 (0.65) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL2477397 | 0.78 | DPP4 (0.64) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL14634819 | 0.78 | DPP4 (0.64) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL14921971 | 0.76 | DPP4 (0.52) | DPP4DPP8DPP9DPP7FAP | |
| Phosphoric Acid SCHEMBL20162034 | 0.75 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL1289271 | 0.74 | DPP4 (0.56) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL14922003 | 0.74 | DPP4 (0.56) | DPP4DPP8DPP9DPP7FAP | |
| Phosphoric Acid SCHEMBL15024109 | 0.73 | DPP4 (0.54) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL14968812 | 0.72 | BRD4 (0.49) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951286-A1 | COMBINED USE OF DPP IV INHIBITORS AND GASTRIN COMPOUNDS | Waratah Pharmaceuticals, Inc. (CA) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007041833-A1 | COMBINED USE OF DPP IV INHIBITORS AND GASTRIN COMPOUNDS | WARATAH PHARMACEUTICALS, INC. (CA) | 2007-04-19 | — | — | WO | disclosed |