Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 20/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | FAP | Q12884 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14921971 | 0.96 | DPP4 (0.52) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL1289241 | 0.77 | DPP4 (0.47) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL15206677 | 0.75 | DPP4 (0.65) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3697380 | 0.75 | DPP4 (0.65) | DPP4DPP8DPP9DPP7ACE | |
| Phosphoric Acid SCHEMBL2570245 | 0.75 | DPP4 (0.70) | DPP4DPP8DPP9DPP7ACE | |
| Phosphoric Acid SCHEMBL2570242 | 0.75 | DPP4 (0.70) | DPP4DPP8DPP9DPP7ACE | |
| Phosphoric Acid SCHEMBL2573060 | 0.74 | DPP4 (0.70) | DPP4DPP8DPP9DPP7ACE | |
| Phosphoric Acid SCHEMBL2573058 | 0.74 | DPP4 (0.70) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL14922003 | 0.73 | DPP4 (0.56) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL5138244 | 0.73 | DPP4 (0.47) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118055778-A | Combination of bitter taste receptor agonist and intestinal signaling compound | 阿达瓦克治疗公司 | 2024-05-17 | — | — | CN | disclosed |
| US-20130158265-A1 | SITAGLIPTIN, SALTS AND POLYMORPHS THEREOF | USV LIMITED (IN) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158265-A1 | SITAGLIPTIN, SALTS AND POLYMORPHS THEREOF | DPP4, DPP3, DPP9 | DPP4 1/4885DPP8 5/4885DPP9 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.