Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094470 | 0.81 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD | |
| SCHEMBL3828857 | 0.77 | ALDH1A1 (0.80) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD | |
| SCHEMBL1879179 | 0.73 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD | |
| SCHEMBL2120000 | 0.73 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD | |
| SCHEMBL3581609 | 0.73 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD | |
| SCHEMBL6398896 | 0.72 | APOBEC3G (0.52) | ALDH1A1KMT2AHSD17B10APOBEC3GTDP1 | |
| SCHEMBL27597440 | 0.72 | KMT2A (0.44) | ALDH1A1SMN1; SMN2KMT2AKDM4EHSD17B10 | |
| SCHEMBL27655633 | 0.72 | KMT2A (0.36) | ALDH1A1SMN1; SMN2KMT2AKDM4EHSD17B10 | |
| SCHEMBL5718020 | 0.72 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD | |
| SCHEMBL27947219 | 0.71 | SLC40A1 (0.50) | ALDH1A1KDM4EHPGDMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384938-B2 | Aqueous formulations of parasiticides for skin applications | BAYER AKTIENGESELLSCHAFT (DE) | 2008-06-10 | — | — | US | claimed |