SCHEMBL5138425

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5930906	0.85	SNCA (0.46)	DCUN1D1TGFBR1MAPK14RIPK2ACVR1B
	SCHEMBL3242826	0.84	TGFBR1 (0.55)	DCUN1D1TGFBR1MAPK14RIPK2ACVR1B
	SCHEMBL5138649	0.81	TGFBR1 (0.41)	DCUN1D1TGFBR1MAPK14RIPK2ACVR1B
	SCHEMBL5138816	0.81	KDM4E (0.43)	DCUN1D1TGFBR1MAPK14RIPK2ACVR1B
	SCHEMBL5139522	0.81	TGFBR1 (0.48)	DCUN1D1TGFBR1MAPK14RIPK2ACVR1B
	SCHEMBL5139510	0.81	SNCA (0.40)	DCUN1D1TGFBR1MAPK14RIPK2ACVR1B
	SCHEMBL5138590	0.79	TGFBR1 (0.39)	DCUN1D1TGFBR1MAPK14RIPK2ACVR1B
	SCHEMBL5138656	0.79	TGFBR1 (0.41)	DCUN1D1TGFBR1MAPK14RIPK2ACVR1B
	SCHEMBL5138410	0.79	TGFBR1 (0.39)	DCUN1D1TGFBR1MAPK14RIPK2ACVR1B
	SCHEMBL5138587	0.79	TGFBR1 (0.39)	DCUN1D1TGFBR1MAPK14RIPK2ACVR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.