⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1703443 | 0.69 | — | — | |
| SCHEMBL22077231 | 0.67 | — | — | |
| SCHEMBL17090769 | 0.64 | — | — | |
| SCHEMBL6986494 | 0.63 | — | — | |
| SCHEMBL18469318 | 0.61 | — | — | |
| SCHEMBL28015655 | 0.61 | MAPT (0.32) | — | |
| SCHEMBL24865844 | 0.59 | MGLL (0.36) | — | |
| SCHEMBL11312340 | 0.59 | — | — | |
| SCHEMBL13865281 | 0.59 | — | — | |
| SCHEMBL346177 | 0.59 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |
| EP-0763036-B1 | [a]-ANNELATED PYRROLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | MERCKLE GMBH (DE) | 2002-09-11 | — | — | EP | disclosed |
| EP-0763037-B1 | [a]-ANNELATED PYRROLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | MERCKLE GMBH (DE) | 2001-11-14 | — | — | EP | disclosed |
| EP-0763037-A1 | [a]-ANNELATED PYRROLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | MERCKLE GMBH (DE) | 1997-03-19 | — | — | EP | disclosed |
| EP-0763036-A1 | [a]-ANNELATED PYRROLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | MERCKLE GMBH (DE) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032972-A1 | [a]-ANNELATED PYRROLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | MERCKLE GMBH (DE) | 1995-12-07 | — | — | WO | disclosed |
| WO-1995032970-A1 | (a)-ANNELATED PYRROLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | MERCKLE GMBH (DE) | 1995-12-07 | — | — | WO | disclosed |