Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139052 | 0.91 | MEN1 (0.45) | MEN1CYP2C9KMT2AMAPTAKR1C1 | |
| SCHEMBL28167765 | 0.75 | MEN1 (0.44) | MEN1CYP2C9KMT2AAKR1C1LMNA | |
| SCHEMBL3392422 | 0.74 | MEN1 (0.42) | MEN1CYP2C9KMT2AAKR1C1LMNA | |
| SCHEMBL3666780 | 0.70 | MEN1 (0.47) | MEN1CYP2C9KMT2AAKR1C1ALDH1A1 | |
| SCHEMBL556387 | 0.68 | MAPT (0.36) | MEN1CYP2C9KMT2AMAPTCYP1A2 | |
| SCHEMBL7890272 | 0.68 | CYP2C9 (0.39) | MEN1CYP2C9KMT2AMAPTMAOA | |
| SCHEMBL5137124 | 0.68 | CYP2C9 (0.43) | MEN1CYP2C9KMT2AMAPTCYP1A2 | |
| SCHEMBL1944655 | 0.68 | MEN1 (0.45) | MEN1CYP2C9KMT2AAKR1C1LMNA | |
| SCHEMBL15656775 | 0.67 | HDAC4 (0.44) | MEN1CYP2C9KMT2AAKR1C1 | |
| SCHEMBL7308988 | 0.67 | CYP2C9 (0.44) | MEN1CYP2C9KMT2AMAPTAKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200499-A1 | Selective Insecticides and/or Acaricides Based on Substituted Cyclic Dicarbonyl Compounds and Safeners | BAYER CROPSCIENCE AG (DE) | 2008-08-21 | — | — | US | disclosed |
| EP-1773126-A1 | SELECTIVE INSECTICIDES AND/OR ACARICIDES BASED ON SUBSTITUTED, CYCLIC DICARBONYL COMPOUNDS AND SAFENERS | Bayer CropScience Aktiengesellschaft (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006008107-A1 | SELECTIVE INSECTICIDES AND/OR ACARICIDES BASED ON SUBSTITUTED, CYCLIC DICARBONYL COMPOUNDS AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200499-A1 | Selective Insecticides and/or Acaricides Based on Substituted Cyclic Dicarbonyl Compounds and Safeners | DDT, AADAC, ACMSD | MEN1 2085/4885CYP2C9 385/4885KMT2A 2611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.