Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28167765 | 0.94 | MEN1 (0.44) | MEN1CYP2C9KMT2AGRIN1GRIN2A | |
| SCHEMBL21452488 | 0.80 | HDAC4 (0.49) | MEN1CYP2C9KMT2AGRIN1GRIN2A | |
| SCHEMBL21452022 | 0.78 | CYP19A1 (0.40) | — | |
| SCHEMBL21452416 | 0.78 | SLC6A3 (0.44) | SLC6A4OPRM1 | |
| SCHEMBL21452493 | 0.76 | GRIN1 (0.46) | MEN1KMT2AGRIN1GRIN2ASLC6A4 | |
| SCHEMBL21452525 | 0.76 | PGR (0.40) | SLC6A4 | |
| SCHEMBL1944655 | 0.76 | MEN1 (0.45) | MEN1CYP2C9KMT2AGRIN1GRIN2A | |
| SCHEMBL15656775 | 0.74 | HDAC4 (0.44) | MEN1CYP2C9KMT2AGRIN1GRIN2A | |
| SCHEMBL15659683 | 0.74 | HDAC4 (0.44) | MEN1CYP2C9KMT2AGRIN1GRIN2A | |
| SCHEMBL5138601 | 0.74 | MEN1 (0.42) | MEN1CYP2C9KMT2ALMNAAKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333023-B1 | Immunogens, antibodies and conjugates to ketamine and its metabolites | RANDOX LAB LTD (GB) | 2010-12-22 | — | — | EP | claimed |
| US-7371829-B2 | Haptens, immunogens, antibodies and conjugates to ketamine and its metabolites | RANDOX LABORATORIES LIMITED (GB) | 2008-05-13 | — | — | US | claimed |
| US-20030224447-A1 | Haptens, immunogens, antibodies and conjugates to ketamine and its metabolites | RANDOX LABORATORIES LIMITED | 2003-12-04 | — | — | US | claimed |
| EP-1333023-A1 | Haptens, immunogens, antibodies and conjugates to ketamine and its metabolites | Randox Laboratories Ltd. (GB) | 2003-08-06 | — | — | EP | claimed |
| EP-1333023-B1 | Immunogens, antibodies and conjugates to ketamine and its metabolites | RANDOX LAB LTD (GB) | 2010-12-22 | — | — | EP | disclosed |
| US-7371829-B2 | Haptens, immunogens, antibodies and conjugates to ketamine and its metabolites | RANDOX LABORATORIES LIMITED (GB) | 2008-05-13 | — | — | US | disclosed |
| US-20030224447-A1 | Haptens, immunogens, antibodies and conjugates to ketamine and its metabolites | RANDOX LABORATORIES LIMITED | 2003-12-04 | — | — | US | disclosed |
| EP-1333023-A1 | Haptens, immunogens, antibodies and conjugates to ketamine and its metabolites | Randox Laboratories Ltd. (GB) | 2003-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030224447-A1 | Haptens, immunogens, antibodies and conjugates to ketamine and its metabolites | HNMT, HLA-DRB1, HLA-A | MEN1 4044/4885CYP2C9 660/4885KMT2A 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.