Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC8A1 | P32418 | 13/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2689406 | 0.88 | SLC8A1 (0.32) | SLC8A1 | |
| SCHEMBL4756646 | 0.86 | SLC8A1 (0.33) | SLC8A1 | |
| SCHEMBL4965120 | 0.85 | BRD4 (0.35) | SLC8A1BRD4 | |
| SCHEMBL4964547 | 0.83 | HTT (0.38) | SLC8A1 | |
| SCHEMBL4962494 | 0.83 | KMT2A (0.37) | SLC8A1 | |
| SCHEMBL4964116 | 0.83 | RAB9A (0.36) | SLC8A1 | |
| SCHEMBL4962487 | 0.83 | KMT2A (0.37) | SLC8A1 | |
| SCHEMBL4964550 | 0.83 | HTT (0.38) | SLC8A1 | |
| SCHEMBL4574531 | 0.82 | SLC8A1 (0.40) | SLC8A1 | |
| SCHEMBL4590624 | 0.82 | SLC8A1 (0.34) | SLC8A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280855-A1 | Process For the Production of Intermediates For the Preparation of Tricyclic Benzimidazoles | NYCOMED GMBH (DE) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280855-A1 | Process For the Production of Intermediates For the Preparation of Tricyclic Benzimidazoles | CYP1B1, CYP1A1, CYP3A4 | SLC8A1 4475/4885BRD4 366/4885CREBBP 1935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.