SCHEMBL5138797

SCHEMBL5138797

CC(C)(C)O[Si](OC(C)(C)C)(OC(C)(C)C)C1CCCCC1.Cc1cc(C)c([Si](OC(C)(C)C)(OC(C)(C)C)OC(C)(C)C)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.32
TAS1R3 Q7RTX0 2/20 0.31
TAS1R1 Q7RTX1 2/20 0.31
TAS1R2 Q8TE23 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5552255 0.80 KDM4E (0.32)
SCHEMBL1130960 0.77
SCHEMBL29026121 0.75
SCHEMBL5029809 0.69 PSMB5 (0.37) PSMB5TAS1R3TAS1R1TAS1R2
SCHEMBL8619206 0.68
SCHEMBL980820 0.66
SCHEMBL5027476 0.62 CYP2A6 (0.35)
SCHEMBL7805531 0.62
SCHEMBL1130733 0.61
SCHEMBL8953546 0.60 NR1H2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1999167-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR Novolen Technology Holdings, C.V. (NL) 2008-12-10 EP disclosed
WO-2007106348-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-09-20 WO disclosed