Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.37 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | KDM4B | O94953 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029969 | 0.81 | ALOX12 (0.35) | KMT2AMEN1TSHRMAPTGAA | |
| SCHEMBL5029824 | 0.73 | NPC1 (0.35) | ALDH1A1KMT2AMEN1LRRK2NPC1 | |
| SCHEMBL11586250 | 0.72 | THRA (0.41) | PSMB5TAS1R3TAS1R1TAS1R2UGT2B17 | |
| SCHEMBL5138797 | 0.69 | PSMB5 (0.32) | PSMB5TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3108980 | 0.66 | ACHE (0.39) | ALDH1A1KMT2AMAPTGAAKDM4E | |
| SCHEMBL14779616 | 0.64 | EBP (0.43) | TAS1R3TAS1R1TAS1R2KMT2AMEN1 | |
| SCHEMBL11148711 | 0.64 | MEN1 (0.41) | ALDH1A1KMT2AMEN1TSHRMAPT | |
| SCHEMBL2724194 | 0.63 | PSMB5 (0.47) | PSMB5TAS1R3TAS1R1TAS1R2UGT2B17 | |
| SCHEMBL9357163 | 0.63 | CYP19A1 (0.35) | KMT2AMEN1NPSR1LRRK2KDM4E | |
| SCHEMBL1452171 | 0.63 | PSMB5 (0.47) | PSMB5TAS1R3TAS1R1TAS1R2UGT2B17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999167-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | Novolen Technology Holdings, C.V. (NL) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007106348-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2007-09-20 | — | — | WO | disclosed |
| US-20070213204-A1 | Ziegler-Natta catalyst with in situ-generated donor | NOVOLEN TECHNOLOGY HOLDINGS C.V. | 2007-09-13 | — | — | US | disclosed |