Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | CCR5 | P51681 | 4/20 | 0.40 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454035 | 0.83 | KDM1A (0.46) | DPP7DPP4FAPDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5105276 | 0.82 | KDM1A (0.45) | DPP7DPP4FAPDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5105273 | 0.82 | KDM1A (0.45) | DPP7DPP4FAPDPP8DPP9 | |
| SCHEMBL14289387 | 0.81 | DPP7 (0.48) | DPP7DPP4FAPDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5106297 | 0.80 | DPP7 (0.47) | DPP7DPP4FAPDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5106295 | 0.80 | DPP7 (0.47) | DPP7DPP4FAPDPP8DPP9 | |
| SCHEMBL14289388 | 0.76 | DPP7 (0.53) | DPP7DPP4FAPDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5107306 | 0.75 | DPP7 (0.52) | DPP7DPP4FAPDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5107311 | 0.75 | DPP7 (0.52) | DPP7DPP4FAPDPP8DPP9 | |
| SCHEMBL14289411 | 0.71 | GRM5 (0.52) | MEP1AMEP1BMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004256-A1 | Amidinophenylalanine Derivatives as Thrombin Inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004256-A1 | Amidinophenylalanine Derivatives as Thrombin Inhibitors | TFPI, SERPINC1, F2 | DPP7 204/4885DPP4 272/4885FAP 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.