Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5105276 | 0.99 | KDM1A (0.45) | KDM1ASLC6A2SLC6A4SLC6A3MEP1A | |
| Hydrochloric Acid SCHEMBL5105273 | 0.99 | KDM1A (0.45) | KDM1ASLC6A2SLC6A4SLC6A3MEP1A | |
| SCHEMBL14289388 | 0.86 | DPP7 (0.53) | KDM1ASLC6A2SLC6A4SLC6A3MEP1A | |
| Hydrochloric Acid SCHEMBL5107311 | 0.85 | DPP7 (0.52) | KDM1ASLC6A2SLC6A4SLC6A3MEP1A | |
| Hydrochloric Acid SCHEMBL5107306 | 0.85 | DPP7 (0.52) | KDM1ASLC6A2SLC6A4SLC6A3MEP1A | |
| SCHEMBL5139527 | 0.83 | DPP7 (0.41) | KDM1ASLC6A2SLC6A4SLC6A3MEP1A | |
| SCHEMBL5103191 | 0.83 | F2 (0.45) | KDM1ASLC6A2SLC6A4SLC6A3MEP1A | |
| SCHEMBL14289411 | 0.82 | GRM5 (0.52) | MEP1AMEP1BMGLLGRM5 | |
| SCHEMBL14289387 | 0.81 | DPP7 (0.48) | KDM1ASLC6A2SLC6A4SLC6A3MEP1A | |
| Hydrochloric Acid SCHEMBL5106295 | 0.81 | DPP7 (0.47) | KDM1ASLC6A2SLC6A4SLC6A3MEP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004256-A1 | Amidinophenylalanine Derivatives as Thrombin Inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2008-01-03 | — | — | US | disclosed |
| US-20080004256-A1 | Amidinophenylalanine Derivatives as Thrombin Inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2008-01-03 | — | — | US | disclosed |
| US-7285547-B2 | Amidinophenylalanine derivatives as thrombin inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2007-10-23 | — | — | US | disclosed |
| US-7285547-B2 | Amidinophenylalanine derivatives as thrombin inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2007-10-23 | — | — | US | disclosed |
| US-7285547-B2 | Amidinophenylalanine derivatives as thrombin inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2007-10-23 | — | — | US | disclosed |
| EP-1355894-B1 | AMIDINOPHENYLALANINE DERIVATIVES AS THROMBIN INHIBITORS | UNIV LJUBLJANI (SI) | 2005-03-16 | — | — | EP | disclosed |
| US-20040048851-A1 | Amidinophenylalanine derivatives as thrombin inhibitors | UNIVERZA V LJUBLJANA (SI) | 2004-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048851-A1 | Amidinophenylalanine derivatives as thrombin inhibitors | TFPI, SERPINC1, F2 | KDM1A 2349/4885SLC6A2 2354/4885SLC6A4 2066/4885 |
| US-20080004256-A1 | Amidinophenylalanine Derivatives as Thrombin Inhibitors | TFPI, SERPINC1, F2 | KDM1A 2886/4885SLC6A2 2493/4885SLC6A4 2208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.