Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 15/20 | 0.62 |
| ▸ | MMP9 | P14780 | 13/20 | 0.62 |
| ▸ | MMP1 | P03956 | 3/20 | 0.58 |
| ▸ | MMP3 | P08254 | 2/20 | 0.58 |
| ▸ | MMP7 | P09237 | 2/20 | 0.58 |
| ▸ | MMP13 | P45452 | 2/20 | 0.58 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.47 |
| ▸ | MMP14 | P50281 | 3/20 | 0.46 |
| ▸ | ADAM10 | O14672 | 2/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | MMP12 | P39900 | 2/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4958777 | 1.00 | MMP2 (0.62) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL14289008 | 0.94 | MMP2 (0.57) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL6073739 | 0.91 | MMP2 (0.61) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL4654917 | 0.85 | MMP2 (0.56) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL4958790 | 0.84 | MMP2 (0.70) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL27202571 | 0.83 | MMP2 (0.53) | MMP2MMP9MMP1MMP3MMP7 | |
| Trifluoroacetic Acid SCHEMBL4958585 | 0.81 | MMP2 (0.64) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL14271497 | 0.81 | MMP2 (0.62) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL7041551 | 0.81 | ITGAV (0.53) | MMP2MMP9MMP14ALDH1A1MMP8 | |
| SCHEMBL27464973 | 0.81 | ITGAV (0.53) | MMP2MMP9MMP14ALDH1A1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321045-B2 | Vitronectin receptor antagonist pharmaceuticals | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2008-01-22 | — | — | US | disclosed |