Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 6/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 5/20 | 0.48 |
| ▸ | MMP9 | P14780 | 5/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041551 | 1.00 | ITGAV (0.53) | ITGAVITGB3ITGA2BALDH1A1MAPT | |
| SCHEMBL8493222 | 0.92 | MMP2 (0.48) | ITGAVITGB3ITGA2BALDH1A1MAPT | |
| SCHEMBL7400840 | 0.90 | SYK (0.46) | ITGAVITGB3ITGA2BALDH1A1MAPT | |
| SCHEMBL7400842 | 0.90 | SYK (0.46) | ITGAVITGB3ITGA2BALDH1A1MAPT | |
| SCHEMBL7752664 | 0.88 | SYK (0.47) | ITGAVITGB3ITGA2BALDH1A1MAPT | |
| SCHEMBL9062856 | 0.87 | ITGAV (0.59) | ITGAVITGB3ITGA2B | |
| SCHEMBL17550404 | 0.84 | MMP9 (0.62) | ALDH1A1MMP2MMP9MMP8MMP12 | |
| SCHEMBL7748751 | 0.84 | SYK (0.42) | ITGAVITGB3ITGA2BALDH1A1MAPT | |
| SCHEMBL7752666 | 0.81 | MMP2 (0.45) | ITGAVITGB3ITGA2BMMP2MMP9 | |
| SCHEMBL5139951 | 0.81 | MMP2 (0.62) | ALDH1A1MAPTMMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138322-A | 2,3-diaminopropionic acid derivative | SUMITOMO PHARMA (JP) | 1996-12-18 | — | — | CN | disclosed |