Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7187320 | 0.82 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1ERN1KDM4E | |
| SCHEMBL7111394 | 0.82 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1ERN1KDM4E | |
| SCHEMBL5087695 | 0.78 | FAAH (0.42) | FAAH | |
| SCHEMBL13191450 | 0.78 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1FAAH | |
| SCHEMBL7907354 | 0.78 | CYP1A2 (0.38) | ALDH1A1L3MBTL1ERN1 | |
| SCHEMBL1421106 | 0.77 | SLC6A4 (0.37) | ALDH1A1FAAHKDM4E | |
| SCHEMBL10385008 | 0.75 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1 | |
| SCHEMBL14920180 | 0.74 | — | — | |
| SCHEMBL6902425 | 0.74 | PTPN1 (0.38) | ALDH1A1L3MBTL1ERN1KDM4E | |
| SCHEMBL30933880 | 0.73 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601348-A4 | COMPOSITIONS AND METHODS WITH ENHANCED THERAPEUTIC ACTIVITY | OXIGENE INC (US) | 2008-12-10 | — | — | EP | disclosed |
| EP-1601348-A2 | COMPOSITIONS AND METHODS WITH ENHANCED THERAPEUTIC ACTIVITY | OXIGENE, INC. (US) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004078126-A2 | COMPOSITIONS AND METHODS WITH ENHANCED THERAPEUTIC ACTIVITY | OXIGENE, INC. (US) | 2004-09-16 | — | — | WO | disclosed |