Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.66 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | TDP2 | O95551 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.41 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxindole SCHEMBL27619236 | 0.83 | AHR (0.95) | AHRPDK2MAPTNPC1MAPK13 | |
| Oxindole SCHEMBL19504 | 0.81 | AHR (1.00) | AHRPDK2MAPTNPC1MAPK13 | |
| Oxindole SCHEMBL29358826 | 0.81 | AHR (1.00) | AHRPDK2MAPTNPC1MAPK13 | |
| Oxindole SCHEMBL1144643 | 0.81 | AHR (1.00) | AHRPDK2MAPTNPC1MAPK13 | |
| Oxindole SCHEMBL5502064 | 0.79 | AHR (0.95) | AHRPDK2MAPTNPC1MAPK13 | |
| Oxindole SCHEMBL5624006 | 0.79 | AHR (0.95) | AHRPDK2MAPTNPC1MAPK13 | |
| Oxindole SCHEMBL15636313 | 0.79 | AHR (0.95) | AHRPDK2MAPTNPC1MAPK13 | |
| Oxindole SCHEMBL8866524 | 0.79 | AHR (0.95) | AHRPDK2MAPTNPC1MAPK13 | |
| Oxindole SCHEMBL4720301 | 0.79 | AHR (0.95) | AHRPDK2MAPTNPC1MAPK13 | |
| Oxindole SCHEMBL1462135 | 0.79 | AHR (0.95) | AHRPDK2MAPTNPC1MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080262056-A1 | Oxindole Oxazolidinones as Antibacterial Agents | PFIZER INC | 2008-10-23 | — | — | US | disclosed |
| CN-101155806-A | Oxindole * oxazolidinones as antibacterial agents | PHARMACIA & UPJOHN CO LTD (US) | 2008-04-02 | — | — | CN | disclosed |
| CN-101155806-A | Oxindole * oxazolidinones as antibacterial agents | PHARMACIA & UPJOHN CO LTD (US) | 2008-04-02 | — | — | CN | disclosed |
| EP-1869029-A1 | AN OXINDOLE OXAZOLIDINONE AS ANTIBACTERIAL AGENT | Pharmacia & Upjohn Company LLC (US) | 2007-12-26 | — | — | EP | disclosed |
| CN-101001853-A | * oxazolidinones containing oxindole as antibacterial agents | PHARMACIA & UPJOHN CO LLC (US) | 2007-07-18 | — | — | CN | disclosed |
| WO-2006106426-A1 | AN OXINDOLE OXAZOLIDINONE AS ANTIBACTERIAL AGENT | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-10-12 | — | — | WO | disclosed |
| US-20060229348-A1 | Oxindole oxazolidinone as antibacterial agent | JOSYULA VARA PRASAD V N | 2006-10-12 | — | — | US | disclosed |
| US-20060229348-A1 | Oxindole oxazolidinone as antibacterial agent | JOSYULA VARA PRASAD V N | 2006-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229348-A1 | Oxindole oxazolidinone as antibacterial agent | OXA1L, MRPL21, RPS27L | AHR 3195/4885PDK2 1227/4885MAPT 4228/4885 |
| US-20080262056-A1 | Oxindole Oxazolidinones as Antibacterial Agents | OXA1L, OXSR1, OXER1 | AHR 2053/4885PDK2 373/4885MAPT 4210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.