Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.41 |
| ▸ | CETP | P11597 | 16/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821109 | 0.86 | CETP (0.40) | TACR1CETP | |
| SCHEMBL5820093 | 0.83 | CETP (0.40) | TACR1CETP | |
| SCHEMBL13697600 | 0.78 | CETP (0.43) | TACR1CETP | |
| SCHEMBL4173923 | 0.76 | TACR1 (0.42) | TACR1CETP | |
| SCHEMBL4193245 | 0.76 | TACR1 (0.49) | TACR1CETP | |
| SCHEMBL5822402 | 0.76 | CETP (0.40) | TACR1CETPKCNH2 | |
| SCHEMBL5134471 | 0.74 | CETP (0.37) | TACR1CETPKCNH2 | |
| SCHEMBL13697576 | 0.74 | TACR1 (0.47) | TACR1CETP | |
| SCHEMBL14602958 | 0.74 | CETP (0.36) | TACR1CETPKCNH2 | |
| SCHEMBL4181093 | 0.73 | TACR1 (0.43) | TACR1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981342-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | Reddy US Therapeutics, Inc. (US) | 2008-10-22 | — | — | EP | claimed |
| WO-2007075194-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDY US THERAPEUTICS, INC. (US) | 2007-07-05 | — | — | WO | claimed |