Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 18/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821109 | 0.83 | CETP (0.40) | CETPTACR1 | |
| SCHEMBL5181413 | 0.79 | KCNH2 (0.34) | CETPTACR1KCNH2 | |
| SCHEMBL5820093 | 0.78 | CETP (0.40) | CETPTACR1 | |
| SCHEMBL4184149 | 0.78 | CETP (0.44) | CETPTACR1 | |
| SCHEMBL13918433 | 0.78 | TACR1 (0.38) | CETPTACR1 | |
| SCHEMBL5823035 | 0.76 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL1601013 | 0.76 | CETP (0.45) | CETPTACR1 | |
| SCHEMBL1600532 | 0.76 | CETP (0.43) | CETPTACR1 | |
| SCHEMBL5624015 | 0.76 | TACR1 (0.35) | CETPTACR1 | |
| SCHEMBL5140629 | 0.76 | TACR1 (0.41) | CETPTACR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848430-A2 | NOVEL BENZYLAMINE DERIVATIVES AS CETP INHIBITORS | Reddy US Therapeutics, Inc. (US) | 2007-10-31 | — | — | EP | claimed |
| WO-2006073973-A2 | NOVEL BENZYLAMINE DERIVATIVES AS CETP INHIBITORS | REDDY US THERAPEUTICS, INC. (US) | 2006-07-13 | — | — | WO | claimed |
| EP-1848430-A2 | NOVEL BENZYLAMINE DERIVATIVES AS CETP INHIBITORS | Reddy US Therapeutics, Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006073973-A2 | NOVEL BENZYLAMINE DERIVATIVES AS CETP INHIBITORS | REDDY US THERAPEUTICS, INC. (US) | 2006-07-13 | — | — | WO | disclosed |