Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | OTC | P00480 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2832674 | 0.90 | — | — | |
| SCHEMBL1359783 | 0.82 | — | — | |
| SCHEMBL1359225 | 0.79 | — | — | |
| SCHEMBL6544656 | 0.78 | GABBR2 (0.64) | GABBR2GABBR1GABRR1ALDH1A1CYP1A2 | |
| SCHEMBL1358501 | 0.78 | GABBR2 (0.64) | PPARDGABBR2GABBR1GABRR1ALDH1A1 | |
| SCHEMBL1359417 | 0.77 | — | — | |
| SCHEMBL17488932 | 0.75 | PPARD (0.39) | PPARDTSHR | |
| SCHEMBL3005950 | 0.73 | — | — | |
| Ethylene Glycol SCHEMBL5490395 | 0.73 | GABBR2 (0.46) | PPARDGABBR2GABBR1GABRR1ALDH1A1 | |
| SCHEMBL338686 | 0.73 | GRM8 (0.53) | TSHRLMNABLMGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161454-A1 | Stabilization Of Polyol Or Polyurethane Compositions Against Thermal Oxidation | CIBA SPECIALTY CHEMICALS CORP. | 2008-07-03 | — | — | US | disclosed |