Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 3/20 | 0.64 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.64 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544636 | 0.90 | GABBR2 (0.64) | GABBR2GABBR1GABRR1LMNABLM | |
| SCHEMBL6544152 | 0.88 | GABBR2 (0.61) | GABBR2GABBR1GABRR1LMNABLM | |
| SCHEMBL341290 | 0.82 | — | — | |
| SCHEMBL2832674 | 0.81 | — | — | |
| Methylamine SCHEMBL5140853 | 0.78 | PPARD (0.44) | GABBR2GABBR1GABRR1LMNABLM | |
| SCHEMBL2353617 | 0.78 | GABBR2 (0.83) | GABBR2GABBR1GABRR1LMNABLM | |
| Sgs-742 SCHEMBL195133 | 0.78 | GABBR2 (1.00) | GABBR2GABBR1GABRR1LMNABLM | |
| SCHEMBL6351264 | 0.76 | GABBR2 (0.87) | GABBR2GABBR1GABRR1LMNABLM | |
| Sgs-742 SCHEMBL6024389 | 0.76 | GABBR2 (0.95) | GABBR2GABBR1GABRR1LMNABLM | |
| SCHEMBL7645156 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372620-A2 | METHODS FOR RESTORING COGNITIVE FUNCTION FOLLOWING SYSTEMIC STRESS | Saegis Pharmaceuticals (US) | 2004-01-02 | — | — | EP | claimed |
| WO-2002074293-A2 | METHODS FOR RESTORING COGNITIVE FUNCTION FOLLOWING SYSTEMIC STRESS | SAEGIS PHARMACEUTICALS INC (US) | 2002-09-26 | — | — | WO | claimed |