SCHEMBL5140862

SCHEMBL5140862

CC1=Cc2c(O)ccc3cccc(c23)C1C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.34
KMT2A Q03164 5/20 0.34
ALDH1A1 P00352 5/20 0.34
GAA P10253 4/20 0.34
HPGD P15428 3/20 0.34
TSHR P16473 3/20 0.34
HSD17B10 Q99714 3/20 0.34
MAPT P10636 3/20 0.34
RAB9A P51151 3/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
CYP1A2 P05177 2/20 0.34
CDK2 P24941 1/20 0.34
APP P05067 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
CYP2C19 P33261 1/20 0.34
SNCA P37840 1/20 0.34
MCL1 Q07820 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1664607 0.74 MEN1 (0.34) MEN1KMT2AALDH1A1GAAHPGD
Water SCHEMBL3478610 0.73 MEN1 (0.33) MEN1KMT2AALDH1A1GAAHPGD
SCHEMBL6533677 0.72 PPARG (0.39) MEN1KMT2AGAATSHRHSD17B10
SCHEMBL9278445 0.68 CDK2 (0.37) MEN1KMT2AALDH1A1GAAHPGD
SCHEMBL27966861 0.68 ALDH1A1 (0.45) MEN1KMT2AALDH1A1GAAHPGD
SCHEMBL3405891 0.67 CDK2 (0.36) MEN1KMT2AALDH1A1GAAHPGD
SCHEMBL28446401 0.67 MEN1 (0.36) MEN1KMT2AMAPT
SCHEMBL8911253 0.66 MEN1 (0.36) MEN1KMT2AALDH1A1GAAHPGD
Dimethylformamide SCHEMBL27399962 0.65 MAPT (0.32) MEN1KMT2AALDH1A1GAAHSD17B10
SCHEMBL2962695 0.65 ALDH1A1 (0.33) MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2001955-A2 NEW POLYARYLENE COMPOSITION AND ARTICLES MADE THEREFROM Solvay Advanced Polymers, L.L.C. (US) 2008-12-17 EP disclosed
WO-2007101852-A2 NEW POLYARYLENE COMPOSITION AND ARTICLES MADE THEREFROM SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2007-09-13 WO disclosed