Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534142 | 0.85 | PPARG (0.38) | PPARGKMT2AMAPTMEN1TDP1 | |
| SCHEMBL6533674 | 0.76 | ESR1 (0.37) | PPARGKMT2AMAPTMEN1TDP1 | |
| SCHEMBL5140862 | 0.72 | MEN1 (0.34) | PPARGKMT2AMAPTMEN1TDP1 | |
| SCHEMBL9282200 | 0.69 | KMT2A (0.38) | PPARGKMT2AMAPTMEN1TDP1 | |
| SCHEMBL6534139 | 0.66 | ESR1 (0.37) | PPARGKMT2AMAPTMEN1ESR1 | |
| SCHEMBL21778844 | 0.65 | F2 (0.50) | KMT2AMAPTMEN1TDP1GAA | |
| SCHEMBL27969264 | 0.63 | ALDH1A1 (0.32) | TDP1TSHRHSD17B10 | |
| SCHEMBL27053129 | 0.63 | GAA (0.41) | PPARGKMT2AMAPTMEN1TDP1 | |
| SCHEMBL24278700 | 0.62 | GAA (0.46) | PPARGKMT2AMAPTMEN1TDP1 | |
| SCHEMBL24279060 | 0.62 | GAA (0.43) | PPARGKMT2AMAPTMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572716-A2 | METHODS FOR SYNTHESIS OF LIQUID CRYSTALS | Southwest Research Institute (US) | 2005-09-14 | — | — | EP | disclosed |
| EP-1572716-A4 | METHODS FOR SYNTHESIS OF LIQUID CRYSTALS | SOUTHWEST RES INST (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2002066493-A2 | METHODS FOR SYNTHESIS OF LIQUID CRYSTALS | SOUTHWEST RESEARCH INSTITUTE (US) | 2002-08-29 | — | — | WO | disclosed |