Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5862781 | 0.88 | ALDH1A1 (0.47) | CYP1A2ALDH1A1KDM4EFDPSLMNA | |
| SCHEMBL7810409 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KDM4EFDPSLMNATRPM8 | |
| SCHEMBL7886018 | 0.84 | CYP1A2 (0.50) | CYP1A2ALDH1A1KDM4EFDPSLMNA | |
| SCHEMBL21025180 | 0.82 | CYP1A2 (0.53) | CYP1A2ALDH1A1KDM4ELMNAMMP8 | |
| SCHEMBL30711682 | 0.82 | CYP4F2 (0.41) | CYP1A2ALDH1A1KDM4ELMNAMMP8 | |
| SCHEMBL5861486 | 0.80 | ALDH1A1 (0.65) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL5861519 | 0.80 | TRPM8 (0.47) | ALDH1A1KDM4EFDPSLMNATRPM8 | |
| SCHEMBL9092131 | 0.80 | CYP1A2 (0.53) | CYP1A2ALDH1A1KDM4EFDPSLMNA | |
| SCHEMBL29694017 | 0.80 | CYP1A2 (0.53) | CYP1A2ALDH1A1KDM4EFDPSLMNA | |
| SCHEMBL7887713 | 0.80 | CYP1A2 (0.53) | CYP1A2ALDH1A1FDPSLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113329996-B | Compounds and methods for treating hedgehog pathway related disorders | 博远医药(苏州)有限公司 | 2023-03-10 | — | — | CN | disclosed |
| EP-1933842-A2 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | Amira Pharmaceuticals, Inc. (US) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007047207-A2 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | AMIRA PHARMACEUTICALS, INC. (US) | 2007-04-26 | — | — | WO | disclosed |