Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.38 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 4/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.33 |
| ▸ | TACR3 | P29371 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829377 | 0.87 | GRM5 (0.38) | GRM5MCHR1FPR2PROKR1 | |
| SCHEMBL3831535 | 0.83 | GRM5 (0.43) | GRM5PANK3ACACB | |
| SCHEMBL14206779 | 0.81 | GRM5 (0.40) | GRM5PANK3MCHR1FPR2PROKR1 | |
| SCHEMBL3829403 | 0.79 | SCD (0.42) | PANK3 | |
| SCHEMBL5105366 | 0.73 | CNR2 (0.39) | TRPV4FPR2PROKR1 | |
| SCHEMBL3825802 | 0.69 | KMT2A (0.44) | PANK3 | |
| SCHEMBL3831560 | 0.68 | GRM5 (0.39) | GRM5PANK3 | |
| SCHEMBL3825833 | 0.67 | GRM5 (0.44) | GRM5 | |
| SCHEMBL3825041 | 0.67 | SCD (0.41) | — | |
| SCHEMBL3826325 | 0.66 | GRM5 (0.40) | GRM5PANK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080182851-A1 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-07-31 | — | — | US | claimed |
| US-20080182851-A1 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-07-31 | — | — | US | disclosed |
| US-20080182851-A1 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182851-A1 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | SCD, SCD5, ACACA | GRM5 2947/4885PANK3 1526/4885MCHR1 4483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.