SCHEMBL5141296

SCHEMBL5141296

C=CCC1=CC(=O)C=CC1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.44
MAOB P27338 3/20 0.44
ACHE P22303 2/20 0.42
BACE1 P56817 1/20 0.42
MAPT P10636 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 2/20 0.36
RECQL P46063 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
MEN1 O00255 1/20 0.36
ALOX12 P18054 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 2/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
ERBB2 P04626 1/20 0.32
BCHE P06276 1/20 0.30
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3807551 0.80 STAT3 (0.33) CYP3A4
SCHEMBL11067925 0.79 MAOA (0.45) MAOAMAOBACHEBACE1MAPT
SCHEMBL9624196 0.76 PTGS1 (0.35)
SCHEMBL9402074 0.74 MAOA (0.41) MAOAMAOBACHEBACE1MAPT
SCHEMBL27522872 0.73 MAOA (0.48) MAOAMAOBACHEBACE1MAPT
SCHEMBL9857340 0.73
SCHEMBL713259 0.72 PTGS1 (0.44) MAOAMAOBACHEBACE1MAPT
SCHEMBL7915011 0.72 ACHE (0.61) MAOAMAOBACHEBACE1MAPT
SCHEMBL15071872 0.72 MAOA (0.64) MAOAMAOBACHEBACE1MAPT
SCHEMBL15978544 0.71 STAT3 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4571435-A SUSTAINED RELEASE TENNESSEE VALLEY AUTHORITY (US) 1986-02-18 US claimed
US-4379939-A Preparation of nitrogen fertilizers from oxalate esters prepared by the oxidative carbonylation of alcohols over noble metal catalysts utilizing regenerable 2,5-cyclohexadiene-1,4-dione oxidants TENNESSEE VALLEY AUTHORITY (US) 1983-04-12 US claimed
JP-8092151-A None JP disclosed
JP-53040728-A None JP disclosed
JP-1011986-A None JP disclosed
JP-5065682-A None JP disclosed
JP-59222436-A None JP disclosed
JP-63068568-A None JP disclosed
CN-116510405-A Equipment for effectively protecting catalyst and purifying method based on equipment 上海策得过滤技术有限公司 2023-08-01 CN disclosed
CN-115769019-A Hydrogen utilization method and hydrogen utilization system 日联海洋株式会社 2023-03-07 CN disclosed
CN-217139304-U Catalyst protector for anthraquinone method hydrogen peroxide production 江苏省化工设计院有限公司 2022-08-09 CN disclosed
JP-S6368568-A P-AMINOPHENOL DERIVATIVE OTSUKA PHARMACEUT FACTORY INC 1988-03-28 JP disclosed
EP-0254259-A2 p-Aminophenol derivatives OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1988-01-27 EP disclosed
US-4617258-A WATER SOLUBLE GROUP 8 COMPOUNDS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-10-14 US disclosed
JP-S59222436-A PRODUCTION OF 2,3-DILOWER ALKOXYL-5-LOWER ALKYL-1,4- BENZOQUINONE SUMITOMO CHEM CO LTD 1984-12-14 JP disclosed
EP-0091788-A2 Silver halide photographic material KONICA CORPORATION (JP) 1983-10-19 EP disclosed
US-4277558-A ANTIFOGGING HYDROQUINONES OR BENZOQUINONES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-07-07 US disclosed
JP-S5340728-A PREPARATION OF QUINONES MITSUBISHI PETROCHEM CO LTD 1978-04-13 JP disclosed
US-4005220-A Hemostatic compositions comprising salts of substituted hydroquinone sulfonic acid LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1977-01-25 US disclosed
US-3975395-A PHOTOGRAPHIC ADDITIVE FUJI PHOTO FILM CO., LTD. (JA) 1976-08-17 US disclosed