Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | F12 | P00748 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27449395 | 0.79 | AKT1 (0.45) | AKT1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL21747960 | 0.78 | AKT1 (0.43) | AKT1HRH1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL17541877 | 0.78 | AKT1 (0.43) | AKT1HRH1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9274317 | 0.78 | AKT1 (0.43) | AKT1HRH1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL60174 | 0.76 | AKT1 (0.42) | AKT1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28788617 | 0.73 | AKT1 (0.39) | AKT1HRH1ALDH1A1HPGDLMNA | |
| SCHEMBL28788613 | 0.73 | AKT1 (0.39) | AKT1HRH1ALDH1A1HPGDLMNA | |
| SCHEMBL15192037 | 0.73 | GPR52 (0.46) | AKT1TDP1 | |
| SCHEMBL1073773 | 0.72 | AKT1 (0.50) | AKT1ALDH1A1LMNAMEN1MAPT | |
| SCHEMBL1073772 | 0.72 | AKT1 (0.50) | AKT1ALDH1A1LMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966290-A2 | POROUS MONOLITHIC ORGANIC COPOLYMER FOR BIOPOLYMER CHROMATOGRAPHY | Leopold-Franzens-Universität Innsbruck (AT) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007073865-A2 | POROUS MONOLITHIC ORGANIC COPOLYMER FOR BIOPOLYMER CHROMATOGRAPHY | LEOPOLD-FRANZENS-UNIVERSITÄT INNSBRUCK (AT) | 2007-07-05 | — | — | WO | disclosed |
| US-20070144972-A1 | Monolithic Organic Copolymer for Biopolymer Chromatography | LEOPOLD-FRANZENS-UNIVERSITAT INNSBRUCK (AT) | 2007-06-28 | — | — | US | disclosed |