SCHEMBL60174

SCHEMBL60174

C=CC(=CCOCC=C(C=C)c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 2/20 0.42
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
DRD2 P14416 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
ALDH1A1 P00352 2/20 0.36
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
THRB P10828 1/20 0.33
CYP3A4 P08684 2/20 0.32
LMNA P02545 2/20 0.32
HPGD P15428 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27449395 0.79 AKT1 (0.45) AKT1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL21747960 0.78 AKT1 (0.43) AKT1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL17541877 0.78 AKT1 (0.43) AKT1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL9274317 0.78 AKT1 (0.43) AKT1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL7123836 0.76 SIGMAR1 (0.51) CHRNB2CHRNB4CHRNA3CHRNA4DRD2
SCHEMBL5141463 0.76 AKT1 (0.42) AKT1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL23501591 0.73 AKT1 (0.35) AKT1DRD2HTR2AHTR2CHTR2B
SCHEMBL15192037 0.73 GPR52 (0.46) AKT1SIGMAR1TDP1
SCHEMBL28788613 0.73 AKT1 (0.39) AKT1HTR2AALDH1A1LMNAHPGD
SCHEMBL28788617 0.73 AKT1 (0.39) AKT1HTR2AALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382367-B2 Polymer electrolyte membrane composed of aromatic polymer membrane base and method for producing the same JAPAN ATOMIC ENERGY AGENCY (JP) 2016-07-05 US disclosed
US-8129074-B2 Crosslinked nano-inorganic particle/polymer electrolyte membrane for membrane electrode assembly JAPAN ATOMIC ENERGY AGENCY (JP) 2012-03-06 US disclosed
US-7993793-B2 Process for producing polymer electrolyte membranes for fuel cells, polymer electrolyte membranes for fuel cells produced by the process, and fuel cell membrane-electrode assemblies using the membranes JAPAN ATOMIC ENERGY AGENCY (JP) 2011-08-09 US disclosed
US-20090325027-A1 POLYMER ELECTROLYTE MEMBRANE COMPOSED OF AROMATIC POLYMER MEMBRANE BASE AND METHOD FOR PRODUCING THE SAME NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) 2009-12-31 US disclosed
US-20070224480-A1 Process for producing polymer electrolyte membranes for fuel cells, polymer electrolyte membranes for fuel cells produced by the process, and fuel cell membrane-electrode assemblies using the membranes JAPAN ATOMIC ENERGY AGENCY (JP) 2007-09-27 US disclosed
US-20070207359-A1 Crosslinked nano-inorganic particle/polymer electrolyte membrane and method for producing same, and membrane electrode assembly using same JAPAN ATOMIC ENERGY AGENCY (JP) 2007-09-06 US disclosed
EP-1137690-B2 PEG-BASED MACROMONOMERS, CHEMICALLY INERT POLYMERS PREPARED THEREFROM AND THE USE OF THESE POLYMERS FOR ORGANIC SYNTHESIS AND ENZYME REACTIONS CARLSBERG AS (DK) 2007-01-24 EP disclosed
EP-1742286-A1 Crosslinked polymer electrolyte fuel cell membranes and their producing process Japan Atomic Energy Agency (JP) 2007-01-10 EP disclosed
US-20060281824-A1 Crosslinked polymer electrolyte fuel cell membranes and their producing process JAPAN ATOMIC ENERGY AGENCY (JP) 2006-12-14 US disclosed
US-7064179-B1 Peg-based macromonomers, chemically inert polymers prepared therefrom and the use of these polymers for organic synthesis and enzyme reactions CARLSBERG A/S (DK) 2006-06-20 US disclosed
EP-1137690-B1 PEG-BASED MACROMONOMERS, CHEMICALLY INERT POLYMERS PREPARED THEREFROM AND THE USE OF THESE POLYMERS FOR ORGANIC SYNTHESIS AND ENZYME REACTIONS CARLSBERG AS (DK) 2004-11-10 EP disclosed
EP-1137690-A2 PEG-BASED MACROMONOMERS, CHEMICALLY INERT POLYMERS PREPARED THEREFROM AND THE USE OF THESE POLYMERS FOR ORGANIC SYNTHESIS AND ENZYME REACTIONS Carlsberg A/S (DK) 2001-10-04 EP disclosed
WO-2000018823-A2 PEG-BASED MACROMONOMERS, CHEMICALLY INERT POLYMERS PREPARED THEREFROM AND THE USE OF THESE POLYMERS FOR ORGANIC SYNTHESIS AND ENZYME REACTIONS CARLSBERG A/S (DK) 2000-04-06 WO disclosed