Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | RPA1 | P27694 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802932 | 0.85 | SLC6A3 (0.44) | IDO1S1PR3S1PR1S1PR4TSHR | |
| SCHEMBL4170313 | 0.84 | MDM2 (0.42) | MDM2S1PR3S1PR1S1PR2S1PR4 | |
| SCHEMBL1008191 | 0.82 | MDM2 (0.40) | MDM2S1PR3S1PR1S1PR2S1PR4 | |
| SCHEMBL6802464 | 0.80 | HDAC4 (0.44) | NPC1TSHR | |
| SCHEMBL6802967 | 0.78 | PARP1 (0.44) | RAB9A | |
| SCHEMBL12498059 | 0.77 | MDM2 (0.46) | MDM2APPCASP1IDO1S1PR3 | |
| SCHEMBL12497645 | 0.77 | MDM2 (0.46) | MDM2APPCASP1IDO1S1PR3 | |
| SCHEMBL21383218 | 0.76 | LMNA (0.51) | IDO1 | |
| SCHEMBL38655195 | 0.76 | APP (0.64) | MDM2APPCASP1IDO1ICMT | |
| SCHEMBL5234318 | 0.76 | APP (0.64) | MDM2APPCASP1IDO1ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297795-B2 | Process for preparation of 4-amino-3-quinolinecarbonitriles | WYETH HOLDINGS CORPORATION (US) | 2007-11-20 | — | — | US | disclosed |