Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3697952 | 0.84 | CYP1A2 (0.59) | CYP1A2TSHRALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL4074230 | 0.83 | CYP1A2 (0.50) | CYP1A2TSHRALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL31145677 | 0.80 | CYP1A2 (0.53) | CYP1A2TSHRALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL267829 | 0.80 | CYP1A2 (0.53) | CYP1A2TSHRALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL14436535 | 0.79 | CYP1A2 (0.54) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL12232403 | 0.79 | CYP1A2 (0.54) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL29834848 | 0.78 | CYP1A2 (0.54) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL2941917 | 0.78 | CYP1A2 (0.54) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL21853757 | 0.77 | CYP1A2 (0.58) | CYP1A2TSHRALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL21853755 | 0.77 | CYP1A2 (0.58) | CYP1A2TSHRALDH1A1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973745-A | Process for obtaining enantiomers of 2-arylpropionic acids | MEDICE CHEM.-PHARM. FABRIK PUTTER GMBH & CO. KG (DE) | 1990-11-27 | — | — | US | claimed |
| US-20070203243-A1 | RESOLUTION OF ALPHA-(PHENOXY) PHENYLACETIC ACID DERIVATIVES | METABOLEX, INC. (US) | 2007-08-30 | — | — | US | disclosed |
| US-7199259-B2 | Resolution of α-(phenoxy)phenylacetic acid derivatives | METABOLEX, INC. (US) | 2007-04-03 | — | — | US | disclosed |
| EP-1635809-A4 | RESOLUTION OF ALPHA-(PHENOXY)PHENYLACETIC ACID DERIVATIVES | METABOLEX INC (US) | 2006-09-27 | — | — | EP | disclosed |
| EP-1635809-A1 | RESOLUTION OF ALPHA-(PHENOXY)PHENYLACETIC ACID DERIVATIVES | Metabolex, Inc. (US) | 2006-03-22 | — | — | EP | disclosed |
| US-20050033084-A1 | Resolution of alpha-(phenoxy)phenylacetic acid derivatives | METABOLEX, INC. (US) | 2005-02-10 | — | — | US | disclosed |
| WO-2004112774-A1 | RESOLUTION OF α-(PHENOXY)PHENYLACETIC ACID DERIVATIVES | METABOLEX, INC. (US) | 2004-12-29 | — | — | WO | disclosed |
| EP-0910573-A1 | NEW AMINO ACID DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | Astra Aktiebolag (SE) | 1999-04-28 | — | — | EP | disclosed |
| WO-1997046577-A1 | NEW AMINO ACID DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | ASTRA AKTIEBOLAG (SE) | 1997-12-11 | — | — | WO | disclosed |
| US-4126617-A | PROPHYLAXIS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-3959289-A | PROPHYLACTICS IN ALLERGIES | THE UPJOHN COMPANY (US) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203243-A1 | RESOLUTION OF ALPHA-(PHENOXY) PHENYLACETIC ACID DERIVATIVES | PAH, HPD, IDUA | CYP1A2 348/4885TSHR 2030/4885ALDH1A1 118/4885 |
| US-20050033084-A1 | Resolution of alpha-(phenoxy)phenylacetic acid derivatives | PAH, PDGFA, PDGFRA | CYP1A2 84/4885TSHR 833/4885ALDH1A1 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.