Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27257058 | 0.79 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL25862811 | 0.75 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL2154404 | 0.73 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL3530585 | 0.73 | MEN1 (0.34) | ALDH1A1 | |
| SCHEMBL338634 | 0.73 | HSD11B1 (0.37) | HSD11B1HSD11B2 | |
| SCHEMBL7597190 | 0.72 | HSD11B1 (0.35) | HSD11B1HSD11B2 | |
| SCHEMBL4818284 | 0.72 | MEN1 (0.36) | ALDH1A1 | |
| SCHEMBL10712719 | 0.70 | — | — | |
| SCHEMBL11373490 | 0.70 | NPC1 (0.39) | ALDH1A1 | |
| SCHEMBL1170206 | 0.69 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976513-B1 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SUNOVION PHARMACEUTICALS INC (US) | 2016-08-24 | — | — | EP | disclosed |
| EP-1976513-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | Sepracor, Inc. (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007081857-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SEPRACOR INC. (US) | 2007-07-19 | — | — | WO | disclosed |