⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13563769 | 0.66 | — | — | |
| SCHEMBL28557895 | 0.64 | — | — | |
| SCHEMBL10793901 | 0.62 | — | — | |
| SCHEMBL21357538 | 0.59 | — | — | |
| SCHEMBL9242242 | 0.57 | GSR (0.36) | — | |
| Nitric Acid SCHEMBL9875239 | 0.56 | CA5A (0.53) | — | |
| SCHEMBL24535831 | 0.55 | — | — | |
| SCHEMBL16238007 | 0.55 | GSR (0.45) | — | |
| SCHEMBL28394988 | 0.55 | ALDH1A1 (0.35) | — | |
| SCHEMBL2573184 | 0.55 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893214-A1 | SYNERGISTIC MODULATION OF FLT3 KINASE USING ALKYLQUINOLINES AND ALKYLQUINAZOLINES | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006135629-A1 | SYNERGISTIC MODULATION OF FLT3 KINASE USING ALKYLQUINOLINES AND ALKYLQUINAZOLINES | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-12-21 | — | — | WO | disclosed |