Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL512766 | 1.00 | APP (0.44) | APPEPHX2LMNAPTGS1PDE4A | |
| SCHEMBL514225 | 0.97 | APP (0.46) | APPEPHX2LMNAPTGS1PDE4A | |
| SCHEMBL513625 | 0.90 | APP (0.48) | APPEPHX2LMNAPTGS1PDE4A | |
| SCHEMBL20894935 | 0.82 | APP (0.46) | APPEPHX2LMNAPTGS1PDE4A | |
| SCHEMBL11412504 | 0.81 | APP (0.41) | APPEPHX2LMNAPTGS1PDE4A | |
| SCHEMBL1270406 | 0.81 | APP (0.61) | APPEPHX2LMNAPTGS1PDE4A | |
| SCHEMBL6692218 | 0.81 | APP (0.61) | APPEPHX2LMNAPTGS1PDE4A | |
| SCHEMBL1270542 | 0.81 | APP (0.61) | APPEPHX2LMNAPTGS1PDE4A | |
| SCHEMBL1270769 | 0.81 | APP (0.61) | APPEPHX2LMNAPTGS1PDE4A | |
| SCHEMBL563101 | 0.81 | APP (0.61) | APPEPHX2LMNAPTGS1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8758777-B2 | Pharmaceutical compositions comprising water-soluble sulfonate-protected nanoparticles and uses thereof | BAR-ILAN UNIVERSITY (IL) | 2014-06-24 | — | — | US | disclosed |
| US-20120027809-A1 | Pharmaceutical compositions comprising water-soluble sulfonate-protected nanoparticles and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2012-02-02 | — | — | US | disclosed |