Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514225 | 0.92 | APP (0.46) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL514218 | 0.90 | APP (0.44) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL512766 | 0.90 | APP (0.44) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL513632 | 0.82 | — | — | |
| SCHEMBL513001 | 0.78 | LMNA (0.53) | APPLMNABLMAPEX1 | |
| SCHEMBL177559 | 0.78 | APP (0.55) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL177845 | 0.76 | APP (0.52) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL2516913 | 0.76 | LMNA (0.50) | APPLMNABLMAPEX1 | |
| SCHEMBL10480105 | 0.76 | ALDH1A1 (0.46) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL2524491 | 0.76 | LMNA (0.50) | APPLMNABLMAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8758777-B2 | Pharmaceutical compositions comprising water-soluble sulfonate-protected nanoparticles and uses thereof | BAR-ILAN UNIVERSITY (IL) | 2014-06-24 | — | — | US | disclosed |
| US-20120027809-A1 | Pharmaceutical compositions comprising water-soluble sulfonate-protected nanoparticles and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2012-02-02 | — | — | US | disclosed |