Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL512766 | 0.97 | APP (0.44) | APPLMNAPTGS1PDE4ASLC6A6 | |
| SCHEMBL514218 | 0.97 | APP (0.44) | APPLMNAPTGS1PDE4ASLC6A6 | |
| SCHEMBL513625 | 0.92 | APP (0.48) | APPLMNAPTGS1PDE4ASLC6A6 | |
| SCHEMBL513632 | 0.80 | — | — | |
| SCHEMBL35183 | 0.80 | APP (0.65) | APPLMNAPTGS1PDE4ASLC6A6 | |
| SCHEMBL513681 | 0.79 | LMNA (0.58) | APPLMNAPDE4ABLMAPEX1 | |
| SCHEMBL20894935 | 0.79 | APP (0.46) | APPLMNAPTGS1PDE4ASLC6A6 | |
| SCHEMBL8592959 | 0.79 | APP (0.52) | APPLMNAPTGS1PDE4ASLC6A6 | |
| SCHEMBL11412504 | 0.78 | APP (0.41) | APPLMNAPTGS1PDE4ASLC6A6 | |
| SCHEMBL16778332 | 0.77 | TSHR (0.60) | APPLMNAPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8758777-B2 | Pharmaceutical compositions comprising water-soluble sulfonate-protected nanoparticles and uses thereof | BAR-ILAN UNIVERSITY (IL) | 2014-06-24 | — | — | US | disclosed |
| US-20120027809-A1 | Pharmaceutical compositions comprising water-soluble sulfonate-protected nanoparticles and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2012-02-02 | — | — | US | disclosed |