Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.59 |
| ▸ | PGR | P06401 | 5/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | IL6 | P05231 | 1/20 | 0.51 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | GLUL | P15104 | 1/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14348465 | 0.91 | NR3C1 (0.63) | NR3C1PGRHIF1ANR1I2LMNA | |
| SCHEMBL11242937 | 0.91 | NR3C1 (0.63) | NR3C1PGRHIF1ANR1I2LMNA | |
| SCHEMBL3982428 | 0.86 | NR3C1 (0.60) | NR3C1PGRHIF1ANR1I2LMNA | |
| SCHEMBL13699675 | 0.83 | NR3C1 (0.61) | NR3C1PGRHIF1ANR1I2LMNA | |
| SCHEMBL450341 | 0.83 | LMNA (0.47) | NR3C1PGRHIF1ANR1I2LMNA | |
| SCHEMBL11238879 | 0.83 | NR3C1 (0.63) | NR3C1PGRHIF1ANR1I2LMNA | |
| SCHEMBL4550100 | 0.83 | NR3C1 (0.63) | NR3C1PGRHIF1ANR1I2LMNA | |
| SCHEMBL11415042 | 0.82 | NR3C1 (0.69) | NR3C1PGRHIF1ANR1I2LMNA | |
| SCHEMBL11415038 | 0.82 | NR3C1 (0.69) | NR3C1PGRHIF1ANR1I2LMNA | |
| SCHEMBL11230636 | 0.81 | NR3C1 (0.65) | NR3C1PGRHIF1ANR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922100-A1 | AN INHALER | GLAXO GROUP LIMITED (GB) | 2008-05-21 | — | — | EP | disclosed |
| WO-2007028992-A1 | AN INHALER | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | WO | disclosed |