SCHEMBL514256

SCHEMBL514256

[CH2]S(=O)(=O)Cc1cccc(Br)c1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.47
IDO1 P14902 2/20 0.46
AGXT P21549 2/20 0.46
MMP2 P08253 1/20 0.44
EGFR P00533 5/20 0.43
ERBB2 P04626 5/20 0.43
MAOB P27338 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30019965 0.83 TAAR1 (0.50) TAAR1IDO1AGXTMMP2EGFR
SCHEMBL1368311 0.83 TAAR1 (0.50) TAAR1IDO1AGXTMMP2EGFR
SCHEMBL10296023 0.82 TAAR1 (0.48) TAAR1IDO1AGXTMMP2EGFR
SCHEMBL2935743 0.80 TAAR1 (0.47) TAAR1IDO1AGXTMMP2EGFR
SCHEMBL514257 0.80 MMP2 (0.48) TAAR1IDO1AGXTMMP2EGFR
Hydrochloric Acid SCHEMBL27989720 0.80 IDO1 (0.48) TAAR1IDO1AGXTMMP2EGFR
SCHEMBL30515516 0.80 MMP2 (0.48) TAAR1IDO1AGXTMMP2EGFR
SCHEMBL1118907 0.80 CA1 (0.57) TAAR1IDO1AGXTMMP2EGFR
SCHEMBL1118911 0.80 TAAR1 (0.47) TAAR1IDO1AGXTMMP2EGFR
SCHEMBL2935741 0.78 TAAR1 (0.46) TAAR1IDO1AGXTMMP2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
WO-2014184071-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
WO-2014184070-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
EP-2420493-A1 HALOALKYLSULFONANILIDE DERIVATIVE Nissan Chemical Industries, Ltd. (JP) 2012-02-22 EP disclosed
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-02-02 US disclosed
EP-2336104-A1 ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2011-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE CBR3, CBR1, HDHD5 TAAR1 677/4885IDO1 2656/4885AGXT 651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.