Known targets — ChEMBL curated mechanism
SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gluconic Acid SCHEMBL29053550 | 0.96 | PDE4A (0.76) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL16370767 | 0.96 | PDE4A (0.76) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL28402789 | 0.88 | LMNA (0.84) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL28658431 | 0.88 | PDE4A (0.83) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL20919813 | 0.88 | PDE4A (0.83) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL9775275 | 0.88 | PDE4A (0.83) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL4896915 | 0.88 | PDE4A (0.83) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL28705777 | 0.87 | PDE4A (0.91) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL28120184 | 0.87 | PDE4A (0.91) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL262276 | 0.87 | PDE4A (0.91) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187146-B | Process for producing 2-methyl-3-buten-2-ol | 浙大宁波理工学院 | 2023-06-23 | — | — | CN | disclosed |
| CN-111187146-A | Method for producing 2-methyl-3-buten-2-ol | 浙江大学宁波理工学院 | 2020-05-22 | — | — | CN | disclosed |
| EP-1752428-B1 | Method for reducing chromium (VI) in cement | GCP APPLIED TECH INC (US) | 2017-03-15 | — | — | EP | disclosed |
| WO-2007021617-A2 | DOSAGE EFFICIENT, STORAGE STABLE COMPOSITIONS FOR REDUCING CHROMIUM (VI) IN CEMENT | W.R. GRACE & CO.-CONN. (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20070034118-A1 | Dosage efficient, storage stable compositions for reducing chromium (VI) in cement | W. R. GRACE & CO.-CONN. | 2007-02-15 | — | — | US | disclosed |
| EP-1752428-A2 | Dosage efficient, storage stable compositions for reducing chromium (VI) in cement | W.R. GRACE & CO.-CONN. (US) | 2007-02-14 | — | — | EP | disclosed |