Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 3/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 5/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18207370 | 0.80 | CYP1A2 (0.48) | CYP2A6ALDH1A1TDP1LMNAHSD17B10 | |
| SCHEMBL9031406 | 0.77 | CYP2A6 (0.43) | CYP2A6F11AHRNR4A2CMA1 | |
| SCHEMBL5544333 | 0.76 | APP (0.42) | TP53TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL48950 | 0.73 | CYP2A6 (0.37) | CYP2A6TSHRALDH1A1TDP1LMNA | |
| SCHEMBL1127451 | 0.73 | CYP2A6 (0.43) | CYP2A6CYP3A4ALDH1A1TDP1ALOX15 | |
| SCHEMBL29644361 | 0.73 | CYP2A6 (0.77) | CYP2A6F11AHRNR4A2CMA1 | |
| SCHEMBL865990 | 0.73 | CYP2A6 (0.77) | CYP2A6F11AHRNR4A2CMA1 | |
| SCHEMBL2473615 | 0.70 | CYP2A6 (0.72) | CYP2A6F11AHRNR4A2CMA1 | |
| SCHEMBL30027002 | 0.70 | CYP2A6 (0.72) | CYP2A6F11AHRNR4A2CMA1 | |
| Hydrochloric Acid SCHEMBL29200223 | 0.70 | CYP2A6 (0.72) | CYP2A6F11AHRNR4A2CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406748-A | Set group and layered product | 富士胶片株式会社 | 2017-11-28 | — | — | CN | disclosed |
| CN-107405870-A | Layered product, temporary bond composition and temporary bond film | 富士胶片株式会社 | 2017-11-28 | — | — | CN | disclosed |
| EP-1285914-B1 | Nr1h4 nuclear receptor binding compounds | PHENEX PHARMACEUTICALS AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| EP-1423370-A4 | FXR NR1H4 NUCLEAR RECEPTOR BINDING COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2007-04-18 | — | — | EP | disclosed |
| EP-1423111-A4 | FXR NR1H4 NUCLEAR RECEPTOR BINDING COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2007-04-18 | — | — | EP | disclosed |
| EP-1423113-A4 | NR1H4 NUCLEAR RECEPTOR BINDING COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2007-04-18 | — | — | EP | disclosed |
| US-20070010562-A1 | Nr1h4 nuclear receptor binding compounds | PHENEX PHARMACEUTICALS AG (DE) | 2007-01-11 | — | — | US | disclosed |
| US-7098336-B2 | FXR NR1H4 nuclear receptor binding compounds | PHENEX PHARMACEUTICALS AG (DE) | 2006-08-29 | — | — | US | disclosed |
| US-20060148876-A1 | Nr3b1 nuclear receptor binding 3-substituted pyrazoles | PHENEX PHARMACEUTICALS AG (DE) | 2006-07-06 | — | — | US | disclosed |
| EP-1536799-B1 | NOVEL 2-AMINO-4-OXOQUINAZOLONES AS LXR NUCLEAR RECEPTOR BINDING COMPOUNDS WITH PARTIAL AGONISTIC PROPERTIES | PHENEX PHARMACEUTICALS AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| WO-1998034115-A1 | 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | disclosed |
| WO-1998002741-A9 | QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES | — | 1998-05-22 | — | — | WO | disclosed |
| WO-1998002741-A1 | QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-01-22 | — | — | WO | disclosed |
| WO-1997016428-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-05-09 | — | — | WO | disclosed |
| EP-0490224-B1 | Derivatives of salicylic aldehyde and salicylic acid, sulfphuranalogs thereof, process and intermediates for their preparation | BASF AG (DE) | 1996-03-13 | — | — | EP | disclosed |
| EP-0527378-B1 | Salicyl(thio)ethers derivatives, process and intermediates for their preparation | BASF AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| US-5362876-A | Intermediates for herbicides or plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1994-11-08 | — | — | US | disclosed |
| US-5308828-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1994-05-03 | — | — | US | disclosed |
| EP-0527378-A1 | Salicyl(thio)ethers derivatives, process and intermediates for their preparation | BASF Aktiengesellschaft (DE) | 1993-02-17 | — | — | EP | disclosed |
| EP-0490224-A2 | Derivatives of salicylic aldehyde and salicylic acid, sulfphuranalogs thereof, process and intermediates for their preparation | BASF Aktiengesellschaft (DE) | 1992-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010562-A1 | Nr1h4 nuclear receptor binding compounds | NR1H4, NR1H2, NR1H3 | CYP2A6 426/4885F11 4628/4885AHR 220/4885 |
| US-20060148876-A1 | Nr3b1 nuclear receptor binding 3-substituted pyrazoles | NR0B1, NR0B2, NR4A3 | CYP2A6 970/4885F11 4063/4885AHR 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.