SCHEMBL1127451

SCHEMBL1127451

Clc1[c]c2cc3ccccc3cc2cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 0.43
ALDH1A1 P00352 4/20 0.37
HSD17B10 Q99714 3/20 0.37
CYP3A4 P08684 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
HIF1A Q16665 2/20 0.37
ALOX15 P16050 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
HBB P68871 1/20 0.37
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CYP1A2 P05177 4/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
GLA P06280 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ACHE P22303 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48950 0.79 CYP2A6 (0.37) CYP2A6ALDH1A1HSD17B10TDP1CYP1A2
SCHEMBL15366386 0.76 ALDH1A1 (0.40) CYP2A6ALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL195377 0.75 ALDH1A1 (0.36) CYP2A6ALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL17707233 0.74 ALDH1A1 (0.37) CYP2A6ALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL1128294 0.74 CYP1A2 (0.43) CYP2A6ALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL1804342 0.74 ALDH1A1 (0.46) CYP2A6ALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL1127747 0.74 CYP2A6 (0.43) CYP2A6ALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL1128123 0.74 CYP2A6 (0.43) CYP2A6ALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL328771 0.74 CYP2A6 (0.43) CYP2A6ALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL10388990 0.74 ALDH1A1 (0.40) CYP2A6ALDH1A1HSD17B10CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569596-B2 Imidazolamino compounds NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2009-08-04 US claimed
US-20060264461-A1 Imidazolamino compounds NATIONAL HEALTH RESEARCH INSTITUTES 2006-11-23 US claimed
US-7109227-B2 Imidazolamino compounds NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2006-09-19 US claimed
US-20040157883-A1 Imidazolamino compounds NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2004-08-12 US claimed
US-20240045330-A1 NEGATIVE PHOTOSENSITIVE COMPOSITION AND PATTERN FORMATION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-08 US disclosed
US-20230236505-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMATION METHOD, AND LAMINATED FILM SAN-APRO LTD. (JP) 2023-07-27 US disclosed
US-20220069354-A1 SULFUR-BASED ELECTROLYTE SOLUTION FOR MAGNESIUM CELL FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2022-03-03 US disclosed
EP-3909943-A1 SULFONIUM SALT, PHOTOACID GENERATOR, CURABLE COMPOSITION AND RESIST COMPOSITION San-Apro Ltd. (JP) 2021-11-17 EP disclosed
EP-3904337-A1 SULFUR-BASED ELECTROLYTE SOLUTION FOR MAGNESIUM CELL FUJIFILM Wako Pure Chemical Corporation (JP) 2021-11-03 EP disclosed
CN-113286781-A Sulfonium salt, photoacid generator, curable composition, and resist composition 三亚普罗股份有限公司 2021-08-20 CN disclosed
EP-3439097-B1 ELECTROLYTE SOLUTION CONTAINING MAGNESIUM IONS FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2020-12-30 EP disclosed
US-10727534-B2 Electrolyte solution containing magnesium ions FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2020-07-28 US disclosed
US-4895587-A Haloacetamide compounds, process for production thereof, and use thereof as herbicide TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1990-01-23 US disclosed
EP-0206251-B1 HALOACETAMIDE COMPOUNDS, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDE TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1988-09-07 EP disclosed
EP-0206251-A1 Haloacetamide compounds, process for production thereof, and use thereof as herbicide TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-12-30 EP disclosed
US-4076537-A Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US disclosed
US-4076530-A Dry photographic copying method for producing Te images FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US disclosed
US-4062685-A ORGANO-TELLURIUM COMPOUND FUJI PHOTO FILM CO., LTD. (JA) 1977-12-13 US disclosed
US-4059432-A A 2-SULFONYLOXYETHYL-PHOSPHONIC OR -THIONOPHOSPHONIC ACID DERIVATIVE MITSUBISHI PETROCHEMICAL CO., LTD. (JA) 1977-11-22 US disclosed
US-4059431-A A 2-SULFONYLOXYETHYL-PHOSPHONIC OR -THIONOPHOSPHONIC ACID DERIVATIVE MITSUBISHI PETROCHEMICAL CO., LTD. (JA) 1977-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10727534-B2 Electrolyte solution containing magnesium ions MLX, PRDX1, PRDX6 CYP2A6 389/4885ALDH1A1 2396/4885HSD17B10 3643/4885
US-20060264461-A1 Imidazolamino compounds CA2, ASIC3, CNR2 CYP2A6 549/4885ALDH1A1 1013/4885HSD17B10 2988/4885
US-20220069354-A1 SULFUR-BASED ELECTROLYTE SOLUTION FOR MAGNESIUM CELL SLC26A3, PRDX4, PRDX2 CYP2A6 1852/4885ALDH1A1 3074/4885HSD17B10 3298/4885
US-20040157883-A1 Imidazolamino compounds CA2, ASIC3, CNR2 CYP2A6 549/4885ALDH1A1 1013/4885HSD17B10 2988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.