Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10991844 | 0.93 | SLC6A4 (0.54) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| Hydrochloric Acid SCHEMBL10995565 | 0.92 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| Hydrochloric Acid SCHEMBL3937 | 0.82 | SLC6A4 (0.52) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL10989062 | 0.78 | SLC6A4 (0.44) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| Oxalic Acid SCHEMBL4054 | 0.77 | SLC6A4 (0.50) | SLC6A4MEN1MITFKMT2A | |
| Oxalic Acid SCHEMBL3500 | 0.77 | MEN1 (0.50) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| SCHEMBL10989251 | 0.75 | SLC6A4 (0.56) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| SCHEMBL10987303 | 0.75 | SLC6A4 (0.56) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| Hydrochloric Acid SCHEMBL10987609 | 0.74 | SLC6A4 (0.57) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| SCHEMBL5083224 | 0.73 | SLC6A2 (0.52) | SLC6A2SLC6A4KCNH2MEN1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133884-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | COMBINATORX, INCORPORATED (US) | 2008-11-06 | — | — | WO | disclosed |