Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Cinnamic Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.50 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL9838235 | 0.86 | TSHR (0.67) | DAOTSHRNAPRTMAPTCES2 | |
| Benzoic Acid SCHEMBL11652723 | 0.86 | TSHR (0.67) | DAOTSHRNAPRTMAPTCES2 | |
| Cinnamic Alcohol SCHEMBL27887623 | 0.85 | PAM (0.58) | PAMMAOBPLIN1LMNAMAPT | |
| Cinnamic Alcohol SCHEMBL891462 | 0.85 | PAM (0.58) | PAMMAOBPLIN1LMNAMAPT | |
| Cinnamic Alcohol SCHEMBL4175503 | 0.85 | PAM (0.58) | PAMMAOBPLIN1LMNAMAPT | |
| Cinnamic Alcohol SCHEMBL39220 | 0.85 | PAM (0.58) | PAMMAOBPLIN1LMNAMAPT | |
| Cinnamic Alcohol SCHEMBL39219 | 0.85 | PAM (0.58) | PAMMAOBPLIN1LMNAMAPT | |
| Cinnamic Alcohol SCHEMBL28583889 | 0.85 | PAM (0.58) | PAMMAOBPLIN1LMNAMAPT | |
| Cinnamic Alcohol SCHEMBL17812926 | 0.84 | PAM (0.59) | PAMMAOBPLIN1LMNAMAPT | |
| (Z)-1,2-Diphenylethene SCHEMBL29118837 | 0.83 | TSHR (0.70) | DAOTSHRNAPRTMAOBPLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10869474-B2 | Fungicidal compositions | UNIVERSITÄT BASEL (CH) | 2020-12-22 | — | — | US | disclosed |
| US-20190200609-A1 | FUNGICIDAL COMPOSITIONS | UNIVERSITÄT BASEL (CH) | 2019-07-04 | — | — | US | disclosed |
| EP-3471542-A1 | FUNGICIDAL COMPOSITIONS | Universität Basel (CH) | 2019-04-24 | — | — | EP | disclosed |
| WO-2017220565-A1 | FUNGICIDAL COMPOSITIONS | UNIVERSITÄT BASEL (CH) | 2017-12-28 | — | — | WO | disclosed |
| EP-3259991-A1 | FUNGICIDAL COMPOSITIONS | Universität Basel (CH) | 2017-12-27 | — | — | EP | disclosed |
| US-7220529-B2 | Photopolymerizable composition and recording material using the same | FUJIFILM CORPORATION (JP) | 2007-05-22 | — | — | US | disclosed |
| US-20050186504-A1 | Photopolymerizable composition and recording material using the same | FUJI PHOTO FILM CO., LTD. | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190200609-A1 | FUNGICIDAL COMPOSITIONS | CBR3, CYP1A1, CYP4F3 | PAM 2192/4885DAO 821/4885TSHR 868/4885 |
| US-10869474-B2 | Fungicidal compositions | CBR3, CYP3A7, CYP3A43 | PAM 2217/4885DAO 931/4885TSHR 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.