Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.45 |
| ▸ | DRD3 | P35462 | 5/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5143959 | 0.95 | ALDH1A1 (0.48) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL5143652 | 0.91 | ALDH1A1 (0.48) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL5142021 | 0.87 | MAPT (0.45) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL5143739 | 0.86 | PRMT5 (0.46) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL5143628 | 0.86 | PRMT5 (0.45) | MEN1KMT2AALDH1A1TSHRPRMT5 | |
| SCHEMBL5144084 | 0.86 | PRMT5 (0.46) | ALDH1A1TSHRPRMT5WDR77CYP2D6 | |
| SCHEMBL5143855 | 0.85 | PRMT5 (0.47) | DRD2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL5145473 | 0.84 | PRMT5 (0.45) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL5144057 | 0.84 | DRD2 (0.48) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL5146452 | 0.83 | PRMT5 (0.48) | DRD2DRD4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217706-B2 | Propanolamine derivatives | ASTELLAS PHARMA INC. (JP) | 2007-05-15 | — | — | US | disclosed |
| EP-1382333-A2 | Use of beta 3 adrenergic receptor agonists in the treatment of dysuria | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-21 | — | — | EP | disclosed |
| US-6495546-B1 | SUCH AS 1-(N-BENZYL-N-(3-METHOXY-6,7,8,9-TETRAHYDRO-5H-BENZO-CYCLOHEPTEN-6-YL)AMINO)-3-PHENOXY-2-PROPANOL; ADRENERGIC RECEPTOR AGONISTS; ANTIULCEROUS, LIPOLYTIC, ANTIURINARY INCONTINENCE AND ANTIPOLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-17 | — | — | US | disclosed |