SCHEMBL5144374

SCHEMBL5144374

CC(=O)c1ccccc1C(C)=NO

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ALDH1A1 P00352 3/20 0.40
LMNA P02545 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
ALOX15 P16050 1/20 0.39
PBRM1 Q86U86 1/20 0.38
NSD2 O96028 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
MCL1 Q07820 1/20 0.38
CA9 Q16790 1/20 0.38
ELANE P08246 2/20 0.38
PRTN3 P24158 1/20 0.38
PDK2 Q15119 1/20 0.38
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9496010 0.84 ALDH1A1 (0.61) KDM4EKMT2AALDH1A1SMN1; SMN2ALOX15
SCHEMBL18640549 0.83 ALDH1A1 (0.48) KDM4EALDH1A1LMNANPC1MAPT
SCHEMBL279655 0.83 ALDH1A1 (0.53) KDM4EMEN1KMT2AALDH1A1LMNA
SCHEMBL9008317 0.80 ALDH1A1 (0.50) KDM4EMEN1KMT2AALDH1A1LMNA
SCHEMBL7596837 0.80 ALDH1A1 (0.50) KDM4EMEN1KMT2AALDH1A1LMNA
SCHEMBL11373632 0.80 ALDH1A1 (0.50) KDM4EMEN1KMT2AALDH1A1LMNA
SCHEMBL9502647 0.79 AKR1C3 (0.59) KMT2AALDH1A1POLBMAPTELANE
SCHEMBL9588781 0.78 ALDH1A1 (0.38) KDM4EMEN1KMT2AALDH1A1LMNA
SCHEMBL3389542 0.78 AKT1 (0.44) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL9520491 0.75 ALDH1A1 (0.50) KDM4EMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100999582-B Photosensitive bottom anti-reflective coatings BREWER SCIENCE INC 2011-05-11 CN disclosed
CN-1672097-B Photosensitive anti-reflective bottom coating BREWER SCIENCE INC 2010-05-12 CN disclosed
EP-1540417-A4 PHOTOSENSITIVE BOTTOM ANTI-REFLECTIVE COATINGS BREWER SCIENCE INC (US) 2007-11-28 EP disclosed
CN-100999582-A Photosensitive bottom anti-reflective coatings BREWER SCIENCE INC (US) 2007-07-18 CN disclosed
US-7108958-B2 Photosensitive bottom anti-reflective coatings BREWER SCIENCE INC. (US) 2006-09-19 US disclosed
CN-1672097-A Photosensitive anti-reflective bottom coating BREWER SCIENCE INC (US) 2005-09-21 CN disclosed
EP-1540417-A2 PHOTOSENSITIVE BOTTOM ANTI-REFLECTIVE COATINGS Brewer Science, Inc. (US) 2005-06-15 EP disclosed
US-20040219456-A1 Photosensitive bottom anti-reflective coatings BREWER SCIENCE, INC. 2004-11-04 US disclosed
WO-2004012239-A2 PHOTOSENSITIVE BOTTOM ANTI-REFLECTIVE COATINGS BREWER SCIENCE, INC. (US) 2004-02-05 WO disclosed