SCHEMBL514446

SCHEMBL514446

CCCCCCN1C=CN(C)C1OS(=O)(=O)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.33
DRD2 P14416 1/20 0.30
DRD1 P21728 1/20 0.30
DRD4 P21917 1/20 0.30
DRD5 P21918 1/20 0.30
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL318768 1.00 EPHX1 (0.33) EPHX1DRD2DRD1DRD4DRD5
SCHEMBL1331130 1.00 EPHX1 (0.33) EPHX1DRD2DRD1DRD4DRD5
SCHEMBL318567 1.00 EPHX1 (0.33) EPHX1DRD2DRD1DRD4DRD5
SCHEMBL318765 1.00 EPHX1 (0.33) EPHX1DRD2DRD1DRD4DRD5
SCHEMBL318176 1.00 EPHX1 (0.33) EPHX1DRD2DRD1DRD4DRD5
SCHEMBL3615951 0.99 EPHX1 (0.31) EPHX1DRD2DRD1DRD4DRD5
SCHEMBL305737 0.94 DRD2 (0.31) DRD2DRD1DRD4DRD5DRD3
SCHEMBL318426 0.90 EPHX1 (0.34) EPHX1DRD2DRD1DRD4DRD5
SCHEMBL319659 0.88 DRD2 (0.34) DRD2DRD1DRD4DRD5DRD3
SCHEMBL1736116 0.87 EPHX1 (0.31) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 414 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12157287-B2 Variable emissivity surfaces THE UNIVERSITY OF MANCHESTER (GB) 2024-12-03 US claimed
US-11567385-B2 Electrochromic device THE BOEING COMPANY (US) 2023-01-31 US claimed
CN-115636957-A Preparation method of ionic liquid gel microspheres and application of ionic liquid gel microspheres as liquid chamber microreactor in oil product desulfurization 辽宁大学 2023-01-24 CN claimed
US-20230017078-A1 Variable Emissivity Surfaces THE UNIVERSITY OF MANCHESTER (GB) 2023-01-19 US claimed
EP-4110607-A1 VARIABLE EMISSIVITY SURFACES The University of Manchester (GB) 2023-01-04 EP claimed
EP-3753973-B1 A METHOD FOR SEALING A GAP BETWEEN ADJOINING OR CONNECTED SOLID SURFACES ON AN AIRCRAFT BOEING CO (US) 2022-09-28 EP claimed
US-11420916-B2 Systems and methods for separation of olefins from mixtures that contain reducing agents BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-08-23 US claimed
US-20220171247-A1 ELECTROCHROMIC DEVICE THE BOEING COMPANY 2022-06-02 US claimed
CN-109280186-B Method and composition for curing the surface of uncured polysulfide rubber 波音公司 2022-05-10 CN claimed
US-11307476-B2 Electrochromic device THE BOEING COMPANY (US) 2022-04-19 US claimed
US-20120263538-A1 SOIL REMEDIATION SYSTEMS AND METHODS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2012-10-18 US claimed
WO-2012085964-A1 SOIL REMEDIATION SYSTEMS AND METHODS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2012-06-28 WO claimed
US-20110013252-A1 COMPOSITION COMPRISING PHOTOCHROMIC DYES IN AN IONIC SOLVENT Essilor International (compagnie Generale D'optiqu e (FR) 2011-01-20 US claimed
US-7718579-B2 Electrochemical deblocking using a hydrazine derivative COMBIMATRIX CORPORATION (US) 2010-05-18 US claimed
EP-1869061-A2 ELECTROCHEMICAL DEBLOCKING SOLUTION FOR ELECTROCHEMICAL OLIGOMER SYNTHESIS ON AN ELECTRODE ARRAY Combimatrix Corporation (US) 2007-12-26 EP claimed
EP-1805206-A2 ELECTROCHEMICAL DEBLOCKING USING A HYDRAZINE DERIVATIVE Combimatrix Corporation (US) 2007-07-11 EP claimed
US-20070034513-A1 Electrochemical deblocking solution for electrochemical oligomer synthesis on an electrode array COMBIMATRIX CORPORATION 2007-02-15 US claimed
WO-2006105037-A2 ELECTROCHEMICAL DEBLOCKING SOLUTION FOR ELECTROCHEMICAL OLIGOMER SYNTHESIS ON AN ELECTRODE ARRAY COMBIMATRIX CORPORATION (US) 2006-10-05 WO claimed
WO-2006031814-A2 ELECTROCHEMICAL DEBLOCKING USING A HYDRAZINE DERIVATIVE COMBIMATRIX CORPORATION (US) 2006-03-23 WO claimed
US-20060054511-A1 Electrochemical deblocking using a hydrazine derivative CUSTOMARRAY, INC. 2006-03-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11420916-B2 Systems and methods for separation of olefins from mixtures that contain reducing agents TXN2, SLC22A8, SLCO4C1 EPHX1 1885/4885DRD2 1266/4885DRD1 1293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.