Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988676 | 0.86 | TSHR (0.53) | NPC1RAB9AHPGDALDH1A1MAPK1 | |
| SCHEMBL9988677 | 0.86 | TSHR (0.53) | NPC1RAB9AHPGDALDH1A1MAPK1 | |
| SCHEMBL10318373 | 0.83 | HTT (0.46) | TSHRBLMNPSR1CYP1A2HTT | |
| SCHEMBL10317018 | 0.83 | HTT (0.46) | TSHRBLMNPSR1CYP1A2HTT | |
| SCHEMBL5462394 | 0.81 | AKR1C3 (0.44) | TSHRBLMNPSR1CYP1A2PTGS2 | |
| SCHEMBL5037803 | 0.81 | NPC1 (0.50) | NPC1RAB9AHPGDALDH1A1MAPK1 | |
| SCHEMBL10318321 | 0.81 | PTGS2 (0.46) | TSHRCYP1A2CYP2C19PTGS2AKR1C3 | |
| SCHEMBL10318257 | 0.81 | PTGS2 (0.46) | TSHRCYP1A2CYP2C19PTGS2AKR1C3 | |
| SCHEMBL11106833 | 0.80 | HSD17B10 (0.47) | TYRBCHEACHETSHRCYP1A2 | |
| SCHEMBL9662938 | 0.80 | ALDH1A1 (0.51) | NPC1RAB9AHPGDALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018116-A1 | COMPOSITIONS COMPRISING 2-HYDROXYCARBOXYLIC ACIDS AND RELATED COMPOUNDS, AND METHODS FOR ALLEVIATING SIGNS OF DERMATOLOGICAL AGING | YU RUEY J (US) | 1992-10-29 | — | — | WO | claimed |
| EP-0273202-A2 | Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. | Van Scott, Eugene J., Dr. (US) | 1988-07-06 | — | — | EP | claimed |
| EP-1633368-A4 | FOAMABLE PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING A DISORDER | STIEFEL LABORATORIES (US) | 2007-03-14 | — | — | EP | disclosed |
| EP-1633368-A2 | FOAMABLE PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING A DISORDER | STIEFEL LABORATORIES, INC. (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004105702-A2 | FOAMABLE PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING A DISORDER | STIEFEL LABORATORIES, INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-4163759-A | Process for preparing aromatic hydroxyaldehydes | HAARMANN & REIMER GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-08-07 | — | — | US | disclosed |